| Friday, October 4th |
| Wheelersburg 21, Minford 20 |
| Waverly 37, West 7 |
| Oak Hill 21, Valley 16 |
| Portsmouth 28, Coal Grove 13 |
| Symmes Valley 7, Green 0 |
| Eastern 49, East 8 |
| Ironton 50, Chesapeake 6 |
| Southeastern 54, Piketon 34 |
| Rock Hill 26, South Point 21 |
| Gallia Academy 28, Fairland 0 |
| Saturday, October 5th |
| Northwest 41, Notre Dame 12 |
