| Friday 9/27 |
| Symmes Valley 47, East 6 |
| Greenup County 45, Notre Dame 0 |
| Valley 21, Northwest 14 (OT) |
| Fairview 26, Green 22 |
| Gallia Academy 45, Portsmouth 28 |
| Minford 28, East Clinton 21 |
| Jackson 35, Wheelersburg 15 |
| Raceland 56, West 15 |
| Waverly 48, Amanda-Clearcreek 13 |
| Paint Valley 56, Piketon 38 |
| McClain 42, Eastern 20 |
| Ironton 38, South Point 2 |
