| Friday |
| Green 40, Manchester 8 |
| Northwest 52, Huntington 16 |
| Portsmouth 40, River Valley 6 |
| West 21, Coal Grove 12 |
| Valley 23, Piketon 7 |
| Minford 45, Greenup County 27 |
| Wheelersburg 34, Ashland 33 |
| Unioto 41, Waverly 14 |
| Southeastern 62, Eastern 26 |
| Oak Hill 20, Rock Hill 0 |
| Chesapeake 49, Symmes Valley 6 |
| Saturday |
| Fisher Catholic 55, Notre Dame 6 |
