Al Swords, 39, of the Lett Terrace Apartments in West Portsmouth, was arrested on Monday in connection with the rape an 8-year-old female.
Sheriff Marty Donini said Swords is related to the victim.
On July 13, a 10- and 11-year-old boy were arraigned in juvenile court and are accused of raping a 5-year-old Wheelersburg girl.
That incident is alleged to have occurred on July 6.
Swords was arrested at his home after detectives executed a search warrant. They were assisted by the Portsmouth Metropolitan Housing Authority security office.
Swords was taken to the Scioto County jail with bail set at $50,000.
He will be arraigned today in Portsmouth Municipal Court.
The sheriff's office will continue to investigate the incident and charges are expected, pen-ding the outcome of a grand jury.
Anyone with information on the case can call the sheriff's department at (740) 355-8245.
JEFF BARRON can be reached at (740) 353-3101, ext. 236.